What is 7-OH Mitragynine?

7-Hydroxy-Mitragynine (7-OH-MG) is a naturally occurring alkaloid found in Mitragyna speciosa (kratom). It is a metabolite of mitragynine and is considered significantly more potent in its effects, especially in relation to pain relief and opioid receptor activity.

How Does 7-Hydroxy-Mitragynine Work?

This alkaloid interacts strongly with opioid receptors, particularly the mu-opioid receptor, contributing to kratom’s analgesic and euphoric effects. Studies suggest that 7-OH-MG has a higher affinity for these receptors than mitragynine, making it one of the most powerful active compounds in kratom.

Effects and Benefits

1. Potent Pain Relief – Stronger than mitragynine, it is effective for managing chronic and acute pain.

2. Euphoria & Mood Enhancement – It can produce feelings of relaxation and well-being.

3. Sedation & Relaxation – Higher doses contribute to sedation, making it useful for stress relief.

Safety and Considerations

Due to its potency, 7-OH-MG has been under scrutiny for its potential for dependency and opioid-like effects. However, its presence in natural kratom leaves is minimal, and concerns often arise with extracted or enhanced products.

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